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In this regard, a key mode of action to explain this relationship is via glucose transporter type 1 (GLUT1) which increases uptake of the oxidized form of ascorbic acid, dehydroascorbate and subsequently depletes glutathione (Yun et al., 2015)

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Absolute quantification of matrix metabolites reveals the dynamics of mitochondrial metabolism

This is because of the generation of ribulose-5-phosphate and eventually ribose-5-phosphate, which can then be a precursor for nucleotide synthesis.